Statistics

Assignment of protein interactors to ROG's

Source	Intractors	Assigned	%	Arbitrary	New	Unassigned	Unique proteins
bind	285482	273695	95.87	0	7782	4005	40766
grid	28218	19295	68.38	8843	3	77	26945
intact	89190	85695	96.08	19	3250	226	39678
mint	80543	77294	95.97	6	2764	479	28055
MPPI	3628	3281	90.44	178	33	136	857
ophid	146423	145408	99.31	103	653	259	9663
All	633484	604668	95.45	9149	14485	5182	77745

Summary of mapping interaction records to RIG's.

Source	Total records	Protein-only interactors	PPI Assigned to RIGID	Unique RIGIDs
bind	193648	93957	91234(97.1019%)	62859(68.8987%)
grid	218165	218165	217902(99.8794%)	142872(65.5671%)
intact	111572	111008	110598(99.6307%)	97012(87.7159%)
mint	104847	104847	103522(98.7363%)	73733(71.2245%)
HPRD	38037	38037	38017(99.9474%)	37980(99.9027%)
ophid	73257	73257	72907(99.5222%)	47318(64.9019%)
MPACT	16504	16504	16286(98.6791%)	13321(81.7942%)
MPPI	1814	1814	1695(93.4399%)	827(48.7906%)
ALL	757844	657589	652161(99.1746%)	475922(72.9762%)

Features of the ROG assignment score and their corresponding character representation

Character	Description of feature (when the value is 1)	Frequency
D	The source database (D) listed in the interaction record is different than what is expected for the given accession for the protein. In specific cases, this difference is tolerated and the assignment is made.	12719(2.0243%)
E	The protein reference was a retired NCBI Identifier. NCBI\'s eUtils (E) were used to retrieve the current accession and/or sequence.	10909(1.7363%)
G	The interaction record\'s reference for the protein was an EntrezGene (G) identifier. The corresponding products of the gene were used to make the assignment.	0(0.0%)
L	More than one possible assignment is possible (see + above). The assignment with the largest (L) SEGUID is arbitrarily chosen (see Methods)	9150(1.4563%)
M	The protein reference listed by the interaction record was a typographical modification (M) of a known accession. In specific cases, this variation is tolerated and the assignment is made.	1882(0.2995%)
+	More than one possible assignment is possible (+). This case may arise in one of three ways. 1) The reference supplied by the interaction record requires updating but more than one possibility exists. For example, Q7XJL8 was found to be a secondary accession in three separate UniProt records (Q3EBZ2, Q6DR20, and Q8GWA9). 2) The secondary references supplied by the interaction record point to more than one unique protein sequence. 3) An EntrezGene identifier is provided in the interaction record as a protein reference. This identifier points to more than one protein product. An attempt is made to resolve this ambiguity as indicated by ROG score features O, X or L (see below).	9172(1.4598%)
N	The protein reference, taxonomy identifier and sequence for the protein as provided in the interaction record are used to make a new entry in the SEGUID table. The protein interactor is assigned the newly (N) generated ROG identifier.	14485(2.3054%)
O	More than one possible assignment is possible (see + above). The assignment chosen has a SEGUID that is identical to the SEGUID of the original (O) sequence provided in the interaction record.	22(0.0035%)
I	The protein reference used was an NCBI GenInfo Identifier (I).	13495(2.1479%)
U	The protein reference listed in the interaction record and used to make the assignment was a secondary UniProt accession and was updated (U) to a primary UniProt accession in order to make the assignment.	20644(3.2857%)
T	The taxonomy (T) identifier for the protein (as supplied by the interaction record) differed from what was found in the protein sequence record. This discrepancy was tolerated and the assignment was made	24056(3.8287%)
V	The protein reference listed by the interaction record contained version (V) information that was ignored. For example, RefSeq accession.version NP_012420.1 was listed but treated as RefSeq accession NP_012420.	0(0.0%)
Q	The protein reference used to make the assignment was of the type \'see-also\'. See PSI-MI Path: entrySet/entry/interactorList/interactor/xref/primaryRef/refType = \'see-also\'.	27(0.0043%)
P	The interaction record\'s primary (P) reference for the protein was used to make the assignment	584548(93.0362%)
S	One of the interaction record\'s secondary (S) references for the protein was used to make the assignment	43754(6.9638%)
X	More than one possible assignment is possible (see + above). The assignment chosen has the same taxonomy (X) identifier as listed in the interaction record	35(0.0056%)