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Interactions available from major taxonomies

NCBI taxonomy identifier	Scientific name	Number of interactions
9606	Homo sapiens	462552
559292	Saccharomyces cerevisiae S288c	108979
7227	Drosophila melanogaster	60885
10090	Mus musculus	38566
40674	Mammalia	36345
4932	Saccharomyces cerevisiae	35561
3702	Arabidopsis thaliana	24946
6239	Caenorhabditis elegans	17843
83333	Escherichia coli K-12	16659
192222	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	11971
10116	Rattus norvegicus	11181
4896	Schizosaccharomyces pombe	9052
381518	Influenza A virus (A/Wilson-Smith/1933(H1N1))	4087
632	Yersinia pestis	3956

Interactions available from major taxonomies (corrected)

NCBI taxonomy identifier	Scientific name	Number of interactions
9606	Homo sapiens	472494
559292	Saccharomyces cerevisiae S288c	122323
7227	Drosophila melanogaster	60888
10090	Mus musculus	35318
3702	Arabidopsis thaliana	24946
6239	Caenorhabditis elegans	17843
83333	Escherichia coli K-12	16450
192222	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	11971
10116	Rattus norvegicus	9679
284812	Schizosaccharomyces pombe 972h-	9387
381518	Influenza A virus (A/Wilson-Smith/1933(H1N1))	4087
632	Yersinia pestis	3956
243276	Treponema pallidum subsp. pallidum str. Nichols	3642
1111708	Synechocystis sp. PCC 6803 substr. Kazusa	3232

Interactions

	BHF_UCL	BIND	BIND_TRANSLATION	BIOGRID	CORUM	DIP	HPIDB	HPRD	I2D_IMEX	INNATEDB	INTACT	INTCOMPLEX	MATRIXDB	MBINFO	MOLCON	MPACT	MPIDB	MPPI	OPHID	REACTOME	SPIKE	UNIPROTPP	VIRUSHOST
BHF_UCL	518	14	16	53	7	40		28	3	10	508	3		1	1			11	53	40	24		2
BIND		62858	49843	20700	171	24290	5	1554	18	141	24309	166	3	8	7	5914	8	285	1683	701	601	449	169
BIND_TRANSLATION			60720	23763	167	25459	7	2284	23	195	25328	121	3	9	9	5857	7	291	2407	858	767	454	194
BIOGRID				324083	155	29717	6	9705	51	729	58547	175	13	20	74	4236		125	6833	5675	4452	1489	9406
CORUM					2607	155	1	154	9	26	362	67	1	2	4			15	239	159	95	51	21
DIP						74638	4	553	25	225	29461	220	5	7	12	6314	62	58	1278	979	393	549	286
HPIDB							725	3			722								3	5	1	5	5
HPRD								40536	18	404	5515	31	23	15	14			107	7243	2186	3253	203	2746
I2D_IMEX									434	10	433	5			2			6	58	40	29	4	2
INNATEDB										4932	658	11	3	2	4			19	639	466	255	52	53
INTACT											224568	446	74	329	211	6747	899	168	10253	2758	8344	5007	20720
INTCOMPLEX												968			1	113	7	7	75	77	20	60	7
MATRIXDB													324					2	32	51	7	1
MBINFO														330	2			1	28	15	11	3	5
MOLCON															212			3	21	24	6	2	2
MPACT																13398						232
MPIDB																	954					2
MPPI																		776	181	67	56	14	11
OPHID																			47464	4504	6734	302	4313
REACTOME																				141818	1231	247	423
SPIKE																					27824	151	3157
UNIPROTPP																						5049	46
VIRUSHOST																							45538
(Exclusive to source)	10	11047	5247	235454	1921	28293	2	24695	3144	124654	416	192	1	1	5396	53	227	27290	131031	15652	28	22752

Interactors

	BHF_UCL	BIND	BIND_TRANSLATION	BIOGRID	CORUM	DIP	HPIDB	HPRD	I2D_IMEX	INNATEDB	INTACT	INTCOMPLEX	MATRIXDB	MBINFO	MOLCON	MPACT	MPIDB	MPPI	OPHID	REACTOME	SPIKE	UNIPROTPP	VIRUSHOST
BHF_UCL	494	209	221	283	175	236	44	206	44	143	494	33	18	14	29		1	70	295	223	252	118	241
BIND		37441	29648	16135	1810	15796	260	2340	231	1209	19047	1334	80	111	125	4201	66	600	2702	1787	2321	2177	2303
BIND_TRANSLATION			36124	17308	1835	16294	281	2806	248	1362	19714	1253	88	120	132	3878	66	605	3075	2017	2591	2153	2528
BIOGRID				51873	2582	15512	420	6413	269	2307	32383	1604	121	131	180	4550	9	499	5880	3362	5484	3080	6001
CORUM					4363	1693	217	1542	216	1041	3780	318	59	82	146		2	408	2248	1616	1931	1063	1980
DIP						25804	241	1772	244	1305	20766	1442	77	104	135	4421	250	412	2541	1744	2145	2225	2252
HPIDB							782	309	44	227	782	25	22	19	27	1	1	60	492	280	416	184	591
HPRD								9841	188	1453	6115	238	97	55	119		7	264	5148	2890	4497	1009	4291
I2D_IMEX									448	171	448	46	17	14	56		2	87	298	217	251	160	254
INNATEDB										3619	3247	153	73	53	95		7	265	2169	1351	1823	674	1942
INTACT											73955	1982	191	273	275	4953	995	730	8287	4576	7192	4642	8991
INTCOMPLEX												2194	30	9	14	1039	37	65	319	332	265	550	266
MATRIXDB													231	7	7		1	17	142	130	113	37	106
MBINFO														273	17	2	1	39	92	74	71	53	81
MOLCON															275			52	191	148	165	115	181
MPACT																4995			1			894	3
MPIDB																	995	1	11	8	10	19	10
MPPI																		833	418	315	342	256	326
OPHID																			9476	3908	6024	1448	6078
REACTOME																				6013	3097	964	3112
SPIKE																					8811	1286	5403
UNIPROTPP																						4642	1419
VIRUSHOST																							10283
(Exclusive to source)	6190	3607	14983	315	2555	1792	109	27173	115	19	24	18	407	773	905	905

Summary of mapping interaction records to RIGs (Table 5)

Source	Total records	Protein-related interactions	PPI assigned to RIGID	%	Unique RIGIDs	%
BHF_UCL	928	915	915	100.00	518	56.61
BIND	157736	91309	90816	99.46	62858	69.21
BIND_TRANSLATION	192923	84138	81773	97.19	60720	74.25
BIOGRID	790004	493818	491294	99.49	324083	65.97
CORUM	2844	2844	2844	100.00	2607	91.67
DIP	78781	77225	77052	99.78	74638	96.87
HPIDB	1458	1405	1405	100.00	725	51.60
HPRD	83022	83022	82983	99.95	40536	48.85
I2D_IMEX	892	891	891	100.00	434	48.71
INNATEDB	17496	17496	7111	40.64	4932	69.36
INTACT	344906	327730	327637	99.97	224568	68.54
INTCOMPLEX	1100	982	982	100.00	968	98.57
MATRIXDB	596	575	575	100.00	324	56.35
MBINFO	542	521	521	100.00	330	63.34
MOLCON	377	375	375	100.00	212	56.53
MPACT	16504	16504	16373	99.21	13398	81.83
MPIDB	1505	1504	1504	100.00	954	63.43
MPPI	1814	1758	1578	89.76	776	49.18
OPHID	73257	73257	73257	100.00	47464	64.79
REACTOME	141996	141996	141993	100.00	141818	99.88
SPIKE	29686	29686	28323	95.41	27824	98.24
UNIPROTPP	8952	8890	8890	100.00	5049	56.79
VIRUSHOST	45540	45540	45539	100.00	45538	100.00
(All)	1992859	1502381	1484631	98.82	797994	53.75

Assignment of protein interactors to ROGs (Table 3)

Source	Protein interactors	Assigned	%	Arbitrary	Matching sequence	New or obsolete sequence	Unassigned	Unique proteins
BHF_UCL	2060	2060	100.00	0	0	0	0	494
BIND	252251	251706	99.78	0	0	0	545	37441
BIND_TRANSLATION	257681	251597	97.64	40883	0	0	6084	36124
BIOGRID	53047	52116	98.24	11433	0	0	931	51873
CORUM	12916	12916	100.00	7	0	0	0	4363
DIP	26633	26551	99.69	2084	0	0	82	25804
HPIDB	3221	3221	100.00	0	0	0	0	782
HPRD	123812	123812	100.00	13563	95615	130	0	9841
I2D_IMEX	1932	1932	100.00	0	0	0	0	448
INNATEDB	40104	24918	62.13	0	0	0	15186	3619
INTACT	265428	265292	99.95	115	39	74	136	73955
INTCOMPLEX	3256	3256	100.00	0	0	0	0	2194
MATRIXDB	1171	1171	100.00	5	0	0	0	231
MBINFO	1134	1134	100.00	0	0	0	0	273
MOLCON	862	862	100.00	0	0	0	0	275
MPACT	40349	40199	99.63	0	0	0	150	4995
MPIDB	3238	3238	100.00	0	0	0	0	995
MPPI	3568	3361	94.20	16	0	0	207	833
OPHID	146514	146514	100.00	405	20	1014	0	9476
REACTOME	283992	283988	100.00	19	0	0	4	6013
SPIKE	65934	64561	97.92	967	0	0	1373	8811
UNIPROTPP	21185	21185	100.00	1	0	0	0	4642
VIRUSHOST	94874	94873	100.00	22	0	0	1	10283
(All)	1705162	1680463	98.55	69520	95674	1218	24699	122677

ROG summary

	BHF_UCL	BIND	BIND_TRANSLATION	BIOGRID	CORUM	DIP	HPIDB	HPRD	I2D_IMEX	INNATEDB	INTACT	INTCOMPLEX	MATRIXDB	MBINFO	MOLCON	MPACT	MPIDB	MPPI	OPHID	REACTOME	SPIKE	UNIPROTPP	VIRUSHOST
P	2060		173353	33822	12875		3221		1932	24918	264204	3256	1166	1134	862		3238			283963	55189	21180	94851
P+IN											6
P+L			19764	746							2												22
P+N											64
P+X			3	2
PD		116272																2996	124085
PD+IN											2
PD+LQ			10197
PD+N																			1014
PD+X		10
PD+XQ			26
PDIQ			732
PDQ			30573
PGD			613	2079																	306
PGD+L			6300	10659							6										962
PGD+X				13
PI											418
PT			2084	2579							1					30579
PT+L			541	1
PTD		84164									1							44	114
PTD+LQ			4022
PTDIQ			13
PTDQ			2492
PTGD			17	1
PTGD+L			21	2
PTI											16
PTM											3
PU			16		34						396									6	8099	4
PU+L			17		7						76		5							19	5
PU+O											23
PU+X			610								2
PUD		7																143	17341
PUD+L																		13	265
PUD+O																			20
PUD+X		60																162	3526
PUT			4								15					2527
PUT+L			21								30											1
PUT+O											16
PUTD		4																	9
PUTD+L																		3	140
PV											7
PV+L											1
S			146	831		12454		115			1
S+L				25		1560		634
S+N											2
S+O								275
S+X						263
SD				1338		4690		3119
SD+L						215		327
SD+N								130
SD+O								11114
SD+X						1173
SGD								680
SGD+L								2124
SGD+O								15462
SI		45114
ST						4557		112								7093
ST+L						243		3767
ST+O								852
STD				18		702		8455
STD+L						5		645
STD+O								28208
STGD								2023
STGD+L								6026
STGD+O								39571
STI		6075
SU			32
SUD						47
SUD+L						33		25
SUD+O								2
SUD+X						568
SUTD						13
SUTD+L						28		15
SUTD+O								131